Royal Air Force Typhoon FGR4s have joined forces with France's air force in a joint strike against an subterranean weapons facility in Syria used by the Islamic State group (IS), according to the UK's MoD.
The location, identified by surveillance, was thought to be storing arms and explosives, the release indicated, and was positioned in hills just above the ancient city of Palmyra in the heart of Syria.
"The RAF jets used Paveway IV guided bombs to strike a series of entry passages down to the site... early reports indicate the strike was effective," the ministry announced.
There was no indication of any civilian impact in the attack conducted Saturday night and every plane involved made a safe return, the ministry further stated.
The British jets were supported by a Voyager tanker plane.
IS - also known as Daesh - enforced extremist governance over significant areas in Iraq and Syria before its territorial defeat in 2019.
"This strike demonstrates British leadership, and determination to operate in unison with our partners, to eradicate any re-emergence of Daesh and their dangerous and violent ideologies in the Middle East," Britain's Defence Chief the minister stated.
RAF aircraft have performed surveillance missions over Syria to "forestall any attempted resurgence" of the group following its defeat at the Baghuz confrontation in the year 2019, the ministry said.
"I extend gratitude to every member of British forces involved in this strike for their skill and their valour," he said. "They were part of thousands of British troops stationed over Christmas and New Year. This operation, to eliminate militants who threaten our way of life, demonstrates how British military are always on standby, throughout the year, keeping Britain secure at home and powerful internationally."
In December, the United States armed forces conducted what it termed a "massive strike" targeting Daesh sites in Syria, after an attack killed two American soldiers and a civilian linguist in the Palmyra area.
The United Nations estimates Daesh still has an estimated 5,000 to 7,000 combatants in Syria and Iraq.